← Resource Center
Weight Loss · 3 min read
What to Expect Your First Month on GLP-1
Week-by-week reality of starting semaglutide or tirzepatide.
Day 1–3
First injection. Some mild nausea by day 2. Appetite quiets within 48 hours.
Week 1
Reduced cravings. Food noise quiets. Some patients lose 2–3 lbs of water weight.
Week 2–3
Appetite suppression deepens. Mild constipation common. Hydrate aggressively.
Week 4
First dose increase week. Mild nausea may return briefly. Average loss: 4–7 lbs.
What's normal
Mild GI symptoms during titration. Significant fatigue or vomiting = call your care team.
Ready?
START YOUR ASSESSMENT
Four minutes. Clinician review within 24 hours. Plan shipped to your door.
Start NowRelated medications
