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Women's Health · 3 min read

What Is HRT (And Is It Safe)?

The hormone-replacement therapy conversation — clarified, with modern data.

What HRT is

Hormone Replacement Therapy restores declining hormones — typically estradiol and progesterone, sometimes testosterone and DHEA.

The safety question

The 2002 WHI study scared a generation off HRT. The data has since been reanalyzed; for women starting HRT under 60 or within 10 years of menopause, the risk-benefit profile is overwhelmingly favorable.

Bioidentical vs. synthetic

Most clinicians today prefer bioidentical hormones. Same molecules your body makes.

Delivery methods

Transdermal (patch, cream, gel) is generally safer than oral. Pellets are not recommended at BestRx — they can't be adjusted once placed.

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