Men's Health · 3 min read
TRT vs Enclomiphene: Which Path Is Right?
Replacement therapy or natural stimulation? The fertility question matters.
How TRT works
TRT delivers exogenous testosterone. Your body responds by reducing its own production — including the fertility signal (LH/FSH).
How enclomiphene works
Enclomiphene stimulates your pituitary to produce more LH/FSH — which tells your testicles to make more T. Fertility is preserved.
Who picks TRT
Men with significantly low T who want fastest, most predictable results, and don't need to preserve fertility.
Who picks enclomiphene
Men with borderline-low T, men who want to preserve fertility, men who don't want exogenous hormones.
Can you switch?
Yes. Many patients start on enclomiphene, evaluate after 12 weeks, and switch if results aren't sufficient.
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