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Skin Care · 3 min read

Hyperpigmentation: Tranexamic Acid and Compounded Protocols

Melasma, sun spots, post-inflammatory marks — here's what actually fades them.

Tranexamic acid

Reduces melanin production. Oral or topical. Strong evidence for melasma.

Hydroquinone

Powerful for limited courses (12 weeks max). Compounded with tretinoin for stronger effect.

Kojic acid, azelaic acid

Gentler adjuncts; safe for longer use.

Compounded approach

BestRx compounds tretinoin + hydroquinone + tranexamic into a single nightly cream for many patients.

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